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Statistical analyses were performed by unpaired two-tailed Students t test

Oligomeric -syn interacts with cellular membranes to accelerate lipid peroxidation and integrates into the cytomembrane, leading to calcium influx, elevated intracellular calcium levels, and subsequent excitotoxicity and ferroptotic cell death ( The process through which -syn oligomeric species trigger the generation of ROS and the peroxidation of lipids also exhibits a reliance on iron

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